Application

(R)-(-)-Phenylephrine hydrochloride has been used:in the preparation and culturing of cardiocytes and fibroblaststo stimulate myocardial strips to measure slice contractionin primary cardiomyocyte culture to show the effect of Kruppel-like factors (KLF) on cardiac hypertrophy in vivoto evaluate the pharmacological response of embryonic stem cell (ESC)-derived cardiomyocytesto pharmacologically rescue GATA (erythroid transcription factor) binding protein 3 (GATA3) null embryo from early embryonic lethality

Biochem/physiol Actions

α₁-adrenoceptor agonist.

Features and Benefits

This compound is featured on the α1-Adrenoceptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

This compound was developed by Johnson & Johnson. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

General description

(R)-(-)-Phenylephrine hydrochloride is an adrenergic agent, which functions as a β-receptor sympathomimetic drug.

Packaging

5, 10, 25, 50, 100 g in glass bottle